Insufficiently degassed mobile phase in HPLC will lead to higher baseline noise, spikes due to air bubbles, and significant drifting and oscillation of the detector signal in HPLC. These phenomena may lead to significant difficulties in integration of peaks and create problems for quantitative analyses. Dissolved gases affect the operation of the pump and may cause strong pulsation and flow rate changes. This results in serious retention time shifts, making analyte identification difficult.
The SunChrom Degasser
eliminates these problems through the efficient degassing of the eluent. Vacuum degassing is an extremely efficient method of degassing mobile phase and provides a number of benefits when compared to the use of ultrasonic and helium degassing.