SunTissuePrep– OVERVIEW
The SunTissuePrep Tissue Section Preparation System
- automates all tissue section preparation steps that were previously performed manually in many small manual steps in tissue sample preparation.
- Deparaffinization, Rehydration, Antigen-Retrieval (HIER) and pH-adjustment steps are performed efficiently, reliably and fully automated
- Relieves laboratory staff from the tedious preparation procedure
- Ensures a maximum reproducibility of your later analyses
Professional Processing of Pathological Samples
Pathological tissue samples of human or animal origin are typically fixed in formalin solution and embedded in paraffin wax to preserve the tissue structure and their characteristic molecular pattern.
These Formalin Fixed and Paraffin Embedded (FFPE) tissue samples can easily be stored at room temperature for years and decades, but for later molecular analysis or staining procedures, this fixation has to be reversed by a labor intensive and cumbersome procedure of many manual individual steps.
SunTissuePrep
Tissue Slide Preparation System for MALDI-MSI
The Device
SunTissuePrep is a benchtop instrument that is available with a tailored cover to allow the handling of harmful solvents like xylenes commonly used for FFPE sample preparation. The instrument cover has an active exhaust air, which is passed through an activated carbon filter and thus allows the operation of the device independent of any laboratory fume hood.
The instrument has three input and output positions for slide holders. Each slide holder has a capacity of four glass slides. In total, the device can process up to 12 glass slides in one run.
In total, the device has ten stirring positions. Each of these positions is equipped with a standard 100 mL glass beaker into which the required liquids such as xylene, ethanol, water or buffer are filled before the start. Magnetic stirring shortens the incubation time at the individual positions and ensures a highly effective deparaffinization, rehydration and pH adjustment of the samples.
The three drying stations accelerate the evaporation of residual liquids on the samples slides. This feature prevents the carryover of solvents and buffers into subsequent positions.
The heat induced antigen retrieval (HIER) is performed in the water bath. The tub of the bath is chemically inert, which allows the use of any kind of buffer systems and even harsh chemicals. In addition, it can easily be removed from the device for cleaning or maintenance purposes.
The washing station is primarily designed for the H&E staining. The user can choose between two different operating programs: Permanent (water) flow or rinsing cycles with individually adjustable incubation times.
